If you are getting an IID Reject Message as:-

(517) Officer Manual Reject Officer reject-Admin-Other. PLEASE PROVIDE ORIGINAL INVOICES, BANK TRANSACTIONS, RECEIPTS ACCOUNTING FOR ALL GOODS ENTERING CANADA. SHIPMENT ON HOLD FOR DOCS AND HEALTH CANADA APPROVAL.

Then you have to call the port and talk to the officer.

Note- Any 500 error codes are a manual office override. That is an officer at the port typing that in.